Women dealing with bone loss are concerned about the side effects like femur fractures and jaw bone death that might occur if they take the osteoporosis drug Fosamax for an extended period of time. The U.S. Food and Drug Administration, based on several recent studies, has concluded that treatment with Fosamax beyond five years is not recommended, and that the occurrence of injury might increase the longer the drug is taken.
Experts have always recommended strength training as the exercise of choice to keep bones strong. Now, according to a soon-to-be-published study that will appear in the Endocrine Society’s Journal of Clinical Endocrinology and Metabolism (JCEM), even low-impact, or minor exercises might be beneficial when performed by pre-menopausal women who need to keep their bones strong.
Physical Activity is Key to Keeping Bones Strong
Physical activity for pre-menopausal women is very effective in reducing sclerostin, a known inhibitor of bone formation. In addition, physical training enhances IGF-1 levels, which have a very positive effect on bone formation.
1,235 randomly selected pre-menopausal women were chosen for this study. Researchers followed up 58 of these women during an eight-week course of physical activity training and compared them with 62 controls. All women were medically examined and measurements were taken for bone mineral density, bone turnover markers and serum sclerostin and IGF-1.
At the conclusion of the study, it was discovered that those women who had more than two hours of physical activity per week had significantly lower levels of serum sclerostin, but had higher IGF-1 levels than those women who had less than two hours of physical activity per week.
“Physical activity training is conceptually simple, inexpensive, and can serve practical purposes including reducing the risk of low bone mass, osteoporosis, and consequently fractures,” said Dr. Mohammed-Salleh M. Ardawi, professor at the Center of Excellence for Osteoporosis Research and Faculty of Medicine at King Abdul Aziz University in Saudi Arabia and lead researcher for this study. “Our study found that even minor changes in physical activity were associated with clear effects on serum levels of sclerostin, IGF-1 and bone turnover markers.”
Check With Your Physician before Embarking on an Exercise Routine
Although Fosamax has helped many people keep the effects of osteoporosis in check, there might be alternatives to the drug. Some osteoporosis patients benefit greatly from exercise, but others might need additional support from a bone-strengthening drug. Only a qualified medical professional can advise whether osteoporosis can be treated without medication. It is important to weigh the risks and benefits of a drug like Fosamax in order to determine whether it is right for you.
RLG Represents Injured Fosamax Users
If you have been taking Fosamax for an extended period of time and have suffered a femur fracture, it could be because of the medication, and you might be eligible for compensation by filing a femur fracture lawsuit against Merck. The lawyers at the Rottenstein Law Group can help. Our Fosamax lawyers have over 25 years of collective experience advocating for clients in consumer product injury and mass tort cases. Please fill out our contact form or call us at 1-877-332-2347, and one of our lawyers will be in touch.
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